Two sample MR report
CBWD1_Endothelial Cell (Endo) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.0244583 | 0.1625945 | 0.8877101 |
| Weighted median | 6 | -0.0767955 | 0.0160650 | 0.0000018 |
| Inverse variance weighted | 6 | -0.0777099 | 0.0128194 | 0.0000000 |
| Simple mode | 6 | -0.0769979 | 0.0219822 | 0.0172340 |
| Weighted mode | 6 | -0.0767573 | 0.0201926 | 0.0126121 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1169984 | 4 | 0.9983542 |
| Inverse variance weighted | 0.5143066 | 5 | 0.9915901 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1037314 | 0.1645684 | 0.5626988 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001815 | 0 | TRUE | 0.2041721 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
